Friday, February 1, 2013

Association Between Periodontal Disease and Chronic Obstructive Pulmonary Disease - A Reality or Just a Dogma

Link to article


Journal of Periodontology; Copyright 2013 DOI: 10.1902/jop.2013.120347


Dr. Kalpak Prafulla Peter * M.D.S , Dr. Bhumika Ramchandra Mute †M.D.S , Dr. Satish Shripad Doiphode ‡ M.D.S , Dr. Suhas Jagannath Bardapurkar M.D, Dr. Mangala Sonawani Borkar ¶ M.D , Mr. Dhananjay Vasant Raje § Ph.D
Name of institution authors currently affiliated to:-
* Assistant Professor, Department of Periodontics, R.K.D.F Dental College and Research Centre, Bhopal, India.
† Assistant Professor, Department of Orthodontics R.K.D.F Dental College and Research Centre, Bhopal, India.
‡ Professor, Department of Periodontics, C.S.M.S.S Dental College and Research Centre, Aurangabad, India.
¶ Professor, Department of Medicine, Government Medical College and Hospital, Aurangabad, India.
§ MDS Bio-Analytics Pvt. Ltd., Nagpur, India.
Name of Institution the work to be affiliated to:-
C.S.M.S.S Dental College and Research Centre, Aurangabad, India.

Background: Since last few years, association between chronic obstructive pulmonary disease (COPD) and periodontal disease has been promulgated. The present study was aimed at determining the association between these two diseases.

Methods: This observational study included 500 individuals consisting of 102 patients (case group) having COPD and 399 individuals as controls. Subjects in case group were well functioning and ambulatory patients having COPD as determined by their history and FEV1 and FVC values (FEV1- forced expiratory volume in 1 second, FVC-forced vital capacity). Periodontal status was evaluated by following five indices: Plaque index (PI), Oral hygiene index (OHI), Gingival index (GI), Probing depth (PD) and Clinical attachment level (CAL). Lung function test was performed by all the patients (case group) and were then graded into mild, moderate, severe and very severe.

Results: Preliminary analysis was performed to identify the covariates in this study. Individuals in case group had significantly higher CAL, PD and OHI (p<0.0001) as compared to control group after adjusting for covariates. A significant negative correlation was observed between FEV1 values and CAL, PD and GI, thus indicating a trend in which severity of lung obstruction increased as these periodontal indices worsened.

Conclusion: Although present study cannot ascertain causal association but provides with substantial evidence that poor periodontal health is associated with obstructive lung disease.

3 comments:

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  2. Such a good post! Thanks for sharing and guess i will be back soon on your blog!

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  3. Thanks for sharing this useful information! Hope that you will continue with the kind of periodontics stuff you are doing.

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